Early and Late Graft Function after Laparoscopic Hand-assisted Donor Nephrectomy for Living Kidney Transplantation: Comparison with Open Donor Nephrectomy
A. Hamza, M. R. Hoda, M. Tajjour, K. Weigand, O. Rettkowski, P. Fornara
Introduction: The laparoscopic donor nephrectomy has become the procedure of choice in the living related kidney transplantation. Longer warm ischemia time and application of pneumoperitoneum have raised questions about the early and late function of the transplant graft. We report on our experience with laparoscopic hand- assisted donor nephrectomy, in particular concerning the graft function compared with open donor nephrectomy.
Patients and methods: This study is a retrospective, non-randomized single-centre analysis. Between 1995 and March 2008, 72 patients with end-stage renal disease have received kidney transplantation from living related donors. Open nephrectomy was performed in 35 donors, whereas 37 donors had undergone laparoscopic hand-assisted nephrectomy. Immediate graft function, and the biochemical marker of glomerular filtration rate (GFR), serum creatinine and serum cystatin C were evaluated one year after the transplantation.
Results: Both the rate of early graft function as well as late function parameters serum creatinine and serum cystatin C one year after transplantation showed no statistically significant difference between the two groups of patients.
Conclusions: Laparoscopic hand-assisted donor nephrectomy is safe and has no negative impact on the graft function compared with open donor nephrectomy.
Key words: kidney transplantation, live donation, donor nephrectomy, laparoscopy, graft function
OA Dr. Amir Hamza
Universitätsklinik und Poliklinik für
06120 Halle (Saale)